Nexguard For Dogs: The Top Flea and Tick Medicine

Nexguard for Dogs

Nexguard for Dogs: Nexgard is a beef-flavored soft chew that kills fleas and ticks. It contains afoxolaner, an insecticide and acaricide that works by overstimulating the central nervous system of parasites, causing them to die. Nexgard starts working within 8 hours and kills 98-100% of fleas within 24 hours. It also kills black-legged ticks, American dog ticks, and lone star ticks.

Nexguard for Dogs

How Nexgard Works to Kill Fleas and Ticks

Nexgard chewable tablets contain afoxolaner, which is in a class of drugs called isoxazolines. After your dog takes Nexgard, the afoxolaner is absorbed into their bloodstream. It then spreads to the tissues and continues to be released from fat cells for up to a month.


When fleas feed on your dog’s blood, they also ingest the afoxolaner. This causes the fleas’ central nervous system to become hyper-excited, leading to uncontrolled nerve transmission and ultimately death. Nexgard starts killing fleas within 4 hours and achieves >90% effectiveness against fleas within 24 hours.


Nexgard also has strong acaricidal effects, meaning it kills ticks. When ticks attach to your dog to feed, the afoxolaner enters the tick’s system and causes loss of movement and feeding, resulting in detachment and death within 24 hours. Nexgard is shown to kill 5 species of ticks commonly found on dogs: deer ticks, American dog ticks, brown dog ticks, lone star ticks and Gulf Coast ticks.

The long-lasting, fast-acting and broad-spectrum power of Nexgard provides comprehensive protection for your dog against dangerous external parasites. With monthly dosing, you can have peace of mind that your furry friend will stay comfortable and itch-free all season long. Nexgard is safe for puppies as young as 8 weeks of age and for breeding, pregnant and lactating dogs. For comprehensive protection, couple Nexgard with a quality heartworm preventative recommended by your vet. Your dog deserves the very best in preventative care, so ask your vet about Nexgard today!

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Benefits of Using Nexgard for Your Dog

1. Treats and Prevents Fleas and Ticks

The main benefit of Nexgard is that it protects your dog against fleas and ticks, including those that may transmit diseases like Lyme disease or Rocky Mountain spotted fever. Nexgard contains afoxolaner, which is in a class of drugs called isoxazolines, that works by blocking nerve transmission in parasites, which results in their death. Nexgard starts killing fleas within 4 to 6 hours and ticks within 24 hours.

2. Convenient Monthly Dosing

Nexgard comes in the form of beef-flavored chewable tablets that most dogs eat like a treat. The tablets are given monthly, making it an easy preventative to administer and fit into your routine. You don’t have to worry about messy topical treatments and your dog won’t mind taking their medication.

3. Safe for Most Dogs

Nexgard has been tested and approved for use in puppies as young as 8 weeks of age and is safe for pregnant or breeding female dogs. As with any medication, some dogs may experience side effects, such as vomiting, itching, lethargy, or diarrhea, but serious adverse reactions are rare. Nexgard should not be used in dogs with a history of seizures. You should always consult your vet before starting any new medication for your dog.

4. Provides Peace of Mind

Using Nexgard regularly can give you peace of mind knowing your dog has comprehensive protection against dangerous parasites. Your dog will be able to enjoy the outdoors and activities with you without the worry of picking up fleas or ticks. By preventing infestations, you also reduce the risk of flea allergy dermatitis and secondary skin infections in your dog. Overall, Nexgard is a safe, effective, and convenient way to protect the health and comfort of your canine companion.

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Potential Side Effects of Nexgard

While Nexgard is generally very safe for most dogs, some may experience mild side effects. The most common side effects are gastrointestinal issues, like diarrhea or vomiting. Nexgard works by disrupting the nervous system of fleas and ticks, and in rare cases, it may cause neurological side effects in dogs like seizures, tremors or hyperactivity.

1. Gastrointestinal Upset

The most likely side effect is stomach upset, like diarrhea, vomiting, or loss of appetite. This is usually temporary, but if symptoms persist for more than a day or two, contact your vet. To reduce the chance of GI issues, give Nexgard with food.

2. Lethargy or Hyperactivity

Some dogs may experience changes in activity level or behavior after starting Nexgard. They may seem more lethargic or sleepy, while others become hyperactive or restless. These effects are usually temporary, but let your vet know if they continue for more than a couple of days.

3. Neurological Effects

Rare, but serious, side effects can include seizures, tremors, or aggression. While these only occur in a tiny percentage of dogs, seek veterinary care immediately if your dog shows these symptoms after starting Nexgard. Your vet may recommend stopping or switching the medication.

The benefits of Nexgard generally far outweigh the risks of side effects for most dogs. However, as with any medication, some dogs may be sensitive or react badly to the active ingredients. Always carefully monitor your dog after starting any new medication and report any serious or persistent side effects to your vet right away. For most dogs, Nexgard is a very safe and effective way to prevent fleas and ticks with minimal side effects. But if your dog does have a bad reaction, there are alternative flea and tick preventatives your vet may recommend.

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How often should I give Nexgard to my dog?

Nexgard is a once-a-month chewable flea and tick treatment. Give one chewable tablet to your dog each month, ideally on the same date. The medication will provide continuous protection against fleas and ticks for a full month. For the best results, give Nexgard year-round, even during months when ticks and fleas are less active.

Is Nexgard safe?

Nexgard is generally very safe for most dogs when used as directed. The active ingredient, afoxolaner, works by overstimulating the central nervous system of fleas and ticks, causing paralysis and death. Nexgard has been thoroughly tested and is approved for use in puppies as young as 8 weeks of age weighing 4 pounds or more. However, as with any medication, side effects may occur in some dogs. The most common side effects are vomiting, decreased appetite, diarrhea, and lethargy.

Can I give Nexgard with other medications?

Nexgard can be used concurrently with heartworm medication and other dewormers. However, do not use Nexgard in conjunction with any product containing afoxolaner or a similar class of insecticide. Always talk to your vet before giving your dog any new medication, to ensure there are no adverse interactions or contraindications.

How long does it take for Nexgard to start working?

Nexgard starts killing fleas within 4 hours and ticks within 8 hours after administration. Full protection against fleas and ticks is achieved within 24-48 hours after giving your dog the Nexgard chewable. However, Nexgard does not repel fleas and ticks, it only kills them once they bite your dog. So, you may still see fleas or ticks on your dog after giving Nexgard. But they should fall off and die within about 24 hours.

Nexgard provides safe, effective protection for your dog against troublesome parasites. By following the directions and dosage recommendations, you’ll keep your furry friend pest-free and ensure a happy, healthy life together.